Chemotherapy is an adjuvant treatment modalty aimed to reduce the overall risk of cancer recurrence. The benefit and need for chemotherapy can vary from patient to patient depending on the stage of cancer, cancer biology, patient baseline health status and relative age of the patient. Stage 3 breast cancers will generally benefit from chemotherapy and omitting it may lead to a high chance of recurrence. Depending on tumour biology and one of which is what we call the receptor status of the tumour ,will dictate if the patient is suitable for endocrine treatment (tablets).